COMPANY

THE LIBS WORLD

BUSINESS DESCRIPTION

DISTINCTIVE FEATURES & BENEFITS

PROCESS INDUSTRIES

PROCESS INDUSTRIES: Distinctive Elemental Analyzer

2007

PROCESS INDUSTRIES: Distinctive Elemental Analyzer

PROCESS MONITORING STEPS

 

IFPAC: Evaluation of Laser-Induced Breakdown Spectroscopy for the monitoring of solid oral dosage forms in Manufacturing

Makoto Yokoyama¹, Martine Tourigny², Kenji Moroshima^1
1Eisai Co., Ltd., Kakamigahara, Gifu, Japan
²Pharma Laser, Boucherville, Quebec, Canada

Application of Near Infrared and Laser-Induced Breakdown Spectroscopy for the determination of an Active in low-dose powder mixtures for inhalation - limitations of standard PAT-tools

Thilo Jahr¹, Michael Walz¹, Andreas Niemöller², François R. Doucet³ and Martine Tourigny^4
1Boehringer Inghelheim Pharma GmbH & Co. KG, Ingelheim, Germany; ²Bruker Optik GmbH, Ellingen, Germany; ³National Research Center of Canada, Boucherville (QC), Canada; ⁴Pharma Laser, Boucherville (QC), Canada

IFPAC: LIBS: A New tool for Rapid Analysis of Materials and Pharmaceutical products

Mohamad Sabsabi ^1
1National Research Council Canada, Industrial Materials Institute, 75 de Mortagne Blvd, Boucherville,Canada

IFPAC: Developing Quantitative Molecular Analysis Approaches for Pharmaceuticals with LIBS using Chemometrics

François R. Doucet¹ , Martine Tourigny² , Mohamad Sabsabi¹ , Robbe C. Lyon³ and Patrick J. Faustino^3
1National Research Council of Canada (IMI), Boucherville (QC), Canada
²Pharma Laser, Boucherville (QC), Canada
³Division of Product Quality Research, CDER, US FDA, Silver Spring, MD, USA

IFPAC: A powerful "plug-and-play" 3D analytical instrument : PharmaLIBS™250

André Blain, eng.President^1
1Pharma Laser, Boucherville (QC), Canada

IFPAC: The Analytical Niche for LIBS in Pharmaceutical Solid-Dose Formulations

John E. Carroll¹, Martine Tourigny^2
1Cadrai Technology Group; ²Pharma Laser, Boucherville (QC), Canada

IFPAC: The Applications of Laser Breakdown Spectroscopy (LIBS) As a Process Analytical Technology (PAT) to Support Early Development in Pharmaceutical Industry

(Presentation unavailable due to confidential content matter)
Elizabeth Kwong, Ph.D.^1
1Merck Research Laboratories Pharmaceutical Research & Development

Laser-Induced Breakdown Spectroscopy: Application to Pharmaceutical Products

Jean-Pierre Monchalin, Optical Techniques Group leader^1
1National Research Council of Canada, Industrial Materials Institute

Application of laser-induced breakdown spectroscopy (LIBS) for the assessment of pharmaceuticals

Patrick J. Faustino, Ph.D.¹ and Francois Doucet, Ph.D.^2
11Center for Drug Evaluation and Research Office of Pharmaceutical Science Division of Product Quality Research
²National Research Council of Canada (IMI), Boucherville (QC), Canada;

2006

Enabling Molecular Analysis with Laser-Induced Breakdown Spectroscopy (LIBS) using Chemometrics

François R. Doucet¹, Martine Tourigny², Patrick J. Faustino³, Robbe C. Lyon³ and Mohamad Sabsabi^1
1National Research Council of Canada (IMI), Boucherville (QC), Canada
²Pharma Laser, Boucherville (QC), Canada
³Division of Product Quality Research, CDER, US FDA, Silver Spring, MD, USA

Monitoring Pharmaceutical Formulations with Laser-Induced Breakdown Spectroscopy using Chemometrics

François R. Doucet¹, Patrick J. Faustino², Martine Tourigny³, Robbe C. Lyon² and Mohamad Sabsabi^1
1National Research Council of Canada (IMI), Boucherville (QC), Canada
²Division of Product Quality Research, CDER, US FDA, Silver Spring, MD, USA
³Pharma Laser, Boucherville (QC), Canada

2005

Monitoring of manufacturing changes and formulation excipients on solid oral dosage forms of furosemide using laser-induced breakdown spectroscopy (LIBS)

L. St-Onge¹, M. Tourigny³, M. Sabsabi¹ and P. Faustino^2
1National Research Council of Canada (IMI), Boucherville (QC), Canada
²Food & Drug Administration (CDER), Silver Spring (MD), U.S.A.
³Pharma Laser, Boucherville (QC), Canada

Recent uses of laser-induced breakdown spectroscopy for the direct analysis of solid and non-solid pharmaceutical products

Louis St-Onge¹, M. Tourigny², M. Sabsabi^1
1 National Research Council of Canada, Industrial Materials Institute, Boucherville, QC, Canada
² Pharma Laser, Boucherville, QC, Canada

2004

Diatomic carbon emission as a structure-specific signal for the quantitation of drugs by laser-induced breakdown spectroscopy (LIBS)

L. St-Onge ¹, Martine Tourigny ², and Mohamad Sabsabi ^1
1 National Research Council of Canada (IMI), 75 de Mortagne Blvd, Boucherville (QC), Canada
² Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Influence of manufacturing changes and formulation excipients on the direct determination of furosemide in solid oral dosage forms using laser-induced breakdown spectroscopy (LIBS)

L. St-Onge¹,*, P. Faustino², M. Tourigny³, M. Sabsabi^1
1 National Research Council of Canada (IMI), Boucherville (QC), Canada;
² Food & Drug Administration (CDER), Silver Spring (MD), U.S.A.;
³ Pharma Laser, Boucherville (QC), Canada

A comparison of elemental analysis techniques requiring no sample preparation: scanning electron microscopy and laser induced breakdown spectroscopy

Darryl Heuser and Dwight S. Walker
GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, USA Received 16th January 2004, Accepted 30th March 2004 First published as an Advance Article on the web 10th June 2004

2003

RIOS, Maribel "Spectroscopy Technique Focuses on Solid Dosage Forms", Pharmaceutical Technology, January 2003, p15-16.

Pharmaceutical Technology JANUARY 2003

Three-dimensional analyses of tablet content and film coating uniformity by laser-induced breakdown spectroscopy (LIBS)

American Laboratory, February 2003, Volume 35, Number 4

2002

Comparison of Near-IR and Laser Induced Breakdown Spectroscopy for Determination of Mg: Stearate in Pharmaceutical Powders and Solid Dosage Forms

Robert L. Green, John P.Higgins, Mark Mowery, Julie Good, Steve Arrivo*, and Robert A. Reed
Merck Research Laboratories, Pharmaceutical Research and Development, West Point, PA
*Pfizer Global Research & Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, MI 48105

Limits of Detection of a Commercial Laser Induced Breakdown Spectroscopy Instrument for Various Elements in Several Tablet Formulations

Yves Mouget, Martine Tourigny, Patrick Gosselin, and Simon Béchard
Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Three dimensional Representation of Tablet Content Uniformity by Laser Induced Breakdown Spectroscopy (LIBS)

Yves Mouget, Martine Tourigny, Patrick Gosselin, and Simon Béchard
Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Quantitative analysis of pharmaceutical products by laser-induced breakdown spectroscopy

L. St-Onge¹, E. Kwong², M. Sabsabi¹,and E.B. Vadas^2
1National Research Council Canada, Industrial Materails Institute, 75 de Mortagne Blvd, Boucherville, Qc, Canada
²Merck Frosst Canada and Co., P.O. Box 1005, Pointe-Claire-Dorval, Qc, Canada

AAPS: Rapid Analysis of Pharmaceutical Capsules by Laser Induced Rapid Analysis of Pharmaceutical Capsules by Laser Induced Breakdown Spectroscopy Breakdown Spectroscopy (LIBS)

P. Gosselin¹, Y. Mouget¹, M. Tourigny¹, S. Béchard^1
1 Pharma Laser, Boucherville (QC), Canada

AAPS: Rapid and Simultaneous Analysis of Various Minerals in Solid Dose Dietary Supplements Dietary Supplements using Laser Induced Breakdown Spectroscopy using Laser Induced Breakdown Spectroscopy

P. Gosselin¹, Y. Mouget¹, M. Tourigny¹, S. Béchard^1
1 Pharma Laser, Boucherville (QC), Canada

2001

Three Dimensional, Multi-Elemental Drug Mapping

Yves Mouget, Martine Tourigny, Patrick Gosselin, and Simon Béchard
Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Rapid At-Line Determination of Lubricant Distribution in Powder Blends Using Laser Induced Breakdown Spectroscopy (LIBS)

Mark D. Mowery ¹, Robert Sing ², John Kirsch ¹, Amir Razighi ¹,Simon Béchard² and Robert A. Reed ^1
1 Merck Research Laboratories, WP78-210, P.O. Box 4, Sumneytown Pike, West Point, PA 19486
² Pharma Laser, 2730 Chicoutimi, Laval, Qc, Canada H7E 1B1

Rapid Determination of Coating Thickness and Uniformity on Compressed Tablets Using Laser Induced Breakdown Spectroscopy (LIBS)

Mark D. Mowery ¹, John Kirsch¹, Amir Razaghi¹, Robert A. Reed¹, Simon Béchard² and Robert Sing^2
1Merck Research Laboratories, WP78-210, P.O. Box 4, Sumneytown Pike, West Point, PA 19486
²Pharma Laser, 2730 Chicoutimi, Laval, Qc, Canada H7E 1B1

Method Development and Validation of Chlorine and Sulfur Containing Active Drug in Tablets Using Laser Induced Breakdown Spectroscopy (LIBS)

Jean-François Archambault ¹, David Yeung¹, Simon Béchard ², Elizabeth B. Vadas ¹, Yves Mouget², Louis St-Onge³ and Elizabeth Kwong^1
1Merck Frosst Canada and Co., P.O. Box 1005, Pointe-Claire-Dorval, Qc, Canada
²Pharma Laser, 75 de Mortagne Blvd, Boucherville, Qc, Canada
³National Research Council Canada, Industrial Materails Institute, 75 de Mortagne Blvd, Boucherville, Qc, Canada

Laser Induced Breakdown Spectroscopy and its Application to the Analysis of Pharmaceutical Products

Produced by Pharmalaser Inc. with contributions from Patrick Gosselin, Université de Montréal, and the National Research Council of Canada, Industrial Materials Institute.

Determination of Blend and Tablet Uniformity in Solid Dosage Forms by Laser Induced Breakdown Spectroscopy (LIBS)

Yves Mouget, Martine Tourigny, Patrick Gosselin, and Simon Béchard
Pharma Laser,75 de Mortagne Blvd, Boucherville (Qc), Canada

The Application of Laser Induced Breakdown Spectroscopy (LIBS) to the Analysis of Pharmaceutical Materials

Yves Mouget, Martine Tourigny and Simon Béchard
Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Rapid Determination of Active Drug, Disintegrant and Lubricant Content in Pharmaceutical Tablets by Laser-Induced Breakdown Spectroscopy

Yves Mouget, Robert Sing, and Simon Béchard
Pharma Laser Inc.,75 boul. De Mortagne, Boucherville, PQ, Canada, J4B 6Y4

The Determination of Coating Thickness Uniformity in Pharmaceutical Tablets by Laser Induced Breakdown Spectroscopy

Yves Mouget, Robert Sing and Simon Béchard
Pharma Laser, 75 de Mortagne Blvd, Boucherville (Qc), Canada

Rapid at-line analysis of coating thickness and uniformity on tablets using laser induced breakdown spectroscopy

Mark D. Mowery ¹, Robert Sing ², John Kirsch ¹, Amir Razighi ¹,Simon Béchard² and Robert A. Reed ^1
1Merck Research Laboratories, WP78-210, P.O. Box 4, Sumneytown Pike, West Point, PA 19486
²Pharma Laser, 2730 Chicoutimi, Laval, Qc, Canada H7E 1B1

1999

Carbon emissions following 1.064um laser ablation of graphite and organic samples in ambient air

L. St-Onge ¹, R. Sing ², S. Béchard² and M. Sabsabi ^1
1National Research Council Canada, Industrial Materials Institute, 75 de Mortagne Blvd, Boucherville,Canada
²Pharma Laser, 75 de Mortagne Blvd, Boucherville, Qc, Canada

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